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姓名： 刘斌 

性别： 男

职称： 特聘教授

学位： 博士

专业：有机化学

电子邮箱：liubin@ncu.edu.cn

研究方向： 过渡金属催化，自由基化学

教育工作经历

教育背景

博士2009.9-2014.7 浙江大学 有机化学 导师：史炳锋 教授

本科 2005.9-2009.7 bwin必赢唯一官方网站 应用化学

工作经历

2021-至今：bwin必赢唯一官方网站，特聘教授

2019.01-2021 Research Scientist II 科罗拉多州立大学，美国 (Colorado State University) 导师：Garret M. Miyake

2017.08-2018.12博士后 科罗拉多州立大学，美国 (Colorado State University) 导师：Garret M. Miyake

2016.05-2017.08 博士后 科罗拉多大学博尔德分校，美国 (University of Colorado Boulder) 导师：Garret M. Miyake

2014.09-2016.04 博士后 浙江大学 导师： 史炳锋/崔孙良 教授

教学简介

科研简介：详情请看课题组主页：https://www.x-mol.com/groups/liu_bin

欢迎本科生加入课题组从事科研训练，欢迎对本课题组感兴趣的研究生报考，联系方式：理科生命大楼B859。

代表性论文及专利

25. Bin Liu, Andrew M. Romine, Camille Z. Rubel, Keary M. Engle, and Bing-Feng Shi Chelation-Assisted, Transition-Metal-Catalyzed Functionalization of Inert C(sp3)–H Bonds. Chem. Rev. 2021. 121, 14957–15074.

24. Liu, B.; Elder, W. Z.; Miyake, G. M. Scalable and Phosphine-Free Conversion of Alcohols to Carbon–Heteroatom Bonds through the Blue Light-Promoted Iodination Reaction. J. Org. Chem. 2020. 85, 3717–3727. (One of the most read articles, March 2020)

23. Liu, B.; Alegre-Requena, J.; Paton, R.; Miyake, G. M. Unconventional Reactivity of Ethynylbenziodoxolone (EBX) Reagents and Thiols: Scope and Mechanism. Chem. Eur. J. 2020, 26, 2386 –2394. (Inside Cover, hot paper)

22. Liu, B.; Lim, C.-H.; Miyake, G. M. Light driven intermolecular charge transfer induced reactivity of ethynylbenziodoxol(on)e (EBX) and phenols. J. Am. Chem. Soc. 2018, 140, 12829−12835.

21. Lim, C.-H.; Kudisch, M.; Liu, B.; Miyake, G. M. C–N Cross-Coupling via Photoexcitation of Nickel–Amine Complexes. J. Am. Chem. Soc. 2018, 140, 7667–7673.

20. Liu, B.; Lim, C.-H.; Miyake, G. M. Transition-Metal-Free, Visible-Light-Promoted C–S Cross-Coupling through Intermolecular Charge Transfer. Synlett 2018, 29, 2449−2455.

19. Liu, B.; Lim, C.-H.; Miyake, G. M. Visible Light-Promoted C-S Cross-Coupling via Intermolecular Charge-Transfer. J. Am. Chem. Soc. 2017, 139, 13616–13619. (1 most read article, October 2017, highlighted in SYNFACTS)

18. Liu, B.; Zhang, Z.-Z.; Li, X.; Shi, B.-F. Nickel(II)-Catalyzed Direct Arylation of Aryl C–H Bonds with Aryl-boron Reagents Directed by a Removable Bidentate Auxiliary. Org. Chem. Front. 2016, 3, 897−900.

17. Liu, B.; Shi, B.-F. γ-Lactone Synthesis via Palladium(II)-Catalyzed Lactonization of Unactivated Methylene C(sp3)–H Bonds. Synlett 2016, 27, 2396–2400.

16. Zhang, Z.-Z.; Liu, B.; Xu, J.-W.; Yan, S.-Y.; Shi, B.-F. Indole Synthesis via Cobalt(III)-Catalyzed Oxidative Coupling of N-Arylureas and Internal Alkynes. Org. Lett. 2016, 18, 1776−1779.

15. Zhao, S.; Liu, B.; Zhan, B.-B.; Zhang, W.-D.; Shi, B.-F. Nickel-Catalyzed Ortho-Arylation of Unactivated (Hetero)aryl C–H Bonds with Arylsilanes Using a Removable Auxiliary. Org. Lett. 2016, 18, 4586−4589.

14. Liu, B; Shi, B.-F. Transition-Metal-Catalyzed Etherification of Unactivated C-H Bonds. Tetrahedron Lett. 2015, 56, 15−22.

13. Liu, B.; Hu, F.; Shi, B.-F. Recent Advances on Ester Synthesis via Transition-Metal-Catalyzed C-H Activation. ACS Catalysis 2015, 5, 1863−1881.

12. Yan, S.-Y.;‡ Liu, Y.-J.;‡ Liu, B.; Liu, Y-H.; Shi, B.-F. Nickel-Catalyzed Thiolation of Unactivated Aryl C–H Bonds: An Efficient Access to Diverse Aryl Sulfides. Chem. Commun. 2015, 51, 4069–4072.

11. Li, B.; Liu, B.; Shi, B.-F. Copper-Catalyzed ortho-Halogenation of Arenes and Heteroarenes Directed by a Removable Auxiliary. Chem. Commun. 2015, 51, 5093–5096.

10. Yan S.-Y.;‡ Liu Y.-J.;‡ Liu B.; Liu Y-H.; Zhang Z-Z.; Shi, B.-F. Nickel-Catalyzed Direct Thiolation of Unactivated C(sp3)-H Bonds with Disulfides. Chem. Commun. 2015, 51, 7341–7344.

9. Zhan, B.-B.; Liu, B.; Shi, B.-F. Recent Progress on Nickel-Catalyzed Direct Functionalization of Unactivated C-H Bonds (in Chinese). Chin. Sci. Bull. 2015, 60, 1–11.

8. Zhang, Z.-Z.; Liu, B.; Wang, C-Y.; Shi, B.-F. Cobalt(III)-Catalyzed C2-Selective C-H Alkynylation of Indoles. Org. Lett. 2015, 17, 4094–4097.

7. Zhao, S.; Chen, F-J.; Liu, B.; Shi, B.-F. Copper-Catalyzed Direct Acyloxylation of C(sp2)-H Bonds with Benzoic Acids. SCIENCE CHINA Chemistry, 2015, 58, 1302–1309.

6. Li, B.; Wang, S-Q.; Liu, B.; Shi, B.-F. Synthesis of Oxazolines from Amides via Palladium-Catalyzed Functionalization of Unactivated C(sp3)-H Bond. Org. Lett. 2015, 17, 1200–1203.

5. Liu, B.; Jiang, H.-Z.; Shi, B.-F. Palladium-Catalyzed Oxidative Olefination of Phenols Bearing Removable Directing Groups under Molecular Oxygen. J. Org. Chem. 2014, 79, 1521–1526.

4. Liu, B.; Jiang, H.-Z.; Shi, B.-F. Palladium-Catalyzed Oxidative Alkoxy- carbonylation of 2-Phenoxypyridine Derivatives with CO and Alcohols. Org. Biomol. Chem. 2014, 12, 2538–2542.

3. Liu, B.; Hu, F.; Shi, B.-F. Synthesis of Sterically Congested Polycyclic Aromatic Hydrocarbons: Rh(III)-Catalyzed Cascade Oxidative Annulation of Aryl Ketoximes with Internal Alkynes by Sequential Cleavage of Multiple C-H Bonds. Adv. Synth. Catal. 2014, 356, 2688–2696.

2. Zhang, B.; Guan, H.-X.; Liu, B.; Shi, B.-F. Transition-Metal-Catalyzed Arylation of Unactivated C(sp3)-H Bonds Assisted by Bidentate Directing Groups. Chin. J. Org. Chem. 2014, 34, 1487–1498.

1. Liu, B.; Shi, B.-F. Efficient Synthesis of Carboxylic Esters via Pd(II)-Catalyzed Direct Alkoxycarbonylation of Arenes with CO and Alcohols. Synlett 2013, 24, 2274–2278.

编写章节

1. Liu, B.; Hu, F.; Shi, B-F. Rh-Catalyzed Synthesis of Oxygen-Containing Heterocycles (chapter 6). Transition Metal-Catalyzed Heterocycle Synthesis via C-H Activation, (Invited chapter), X. F. Wu (Ed.), Wiley, 2016, pp 161-186.

2. Liu, B.; Han, Y.-Q.; Shi, B.-F. Palladium-Catalyzed Arylation of Unactivated sp3 C-H Bond. Strategies for Palladium-Catalyzed Non-Directed and Directed C-H Bond Functionalization (Debabrata Maiti and Anant Kapdi, Eds), Elsevier, 2017, pp 167-203.

3. Yan, S.-Y.; Liu, B.; Shi, B.-F. Substrate-Controlled Transformation– Diastereoselective Functionalization in C-H Activation for Asymmetric Synthesis (Eds: Colobert, F.; Wencel-Delord, J.), Wiley-VCH, Weinheim, September 2019, pp 107-130

申请专利

1. Miyake, G. M.; Liu, B.; Lim, C.-H. Photocatalyst-free, light-induced carbon-sulfur cross-coupling methods. US20180370911A1.

2. Miyake, G. M.; Lim, C.-H.; Kudisch, M.; Liu, B. Methods for forming aryl carbon-nitrogen bonds using light and photoreactors useful for conducting such reactions. US20190345122A1.