Name: Pengcheng Huang

Gender: Male

Job title: Professor

Email Address: pchuang@ncu.edu.cn

Education and Work Experience：

2018.09-2019.09 Department of Chemistry and Chemical Biology, Rutgers University, USA, Visiting Scholar (Co-Advisor: Prof. Jing Li)

2017.12-2022.12 School of Chemistry and Chemical Engineering, Nanchang University, Associate Professor

2014.07-2017.12 College of Chemistry, Nanchang University, Lecturer

2009.09-2014.07 Institute of Chemistry, Chinese Academy of Sciences, Doctoral degree (Supervisor: Prof. Lanqun Mao)

Teaching：

(1) Undergraduate Course: Instrumental Analysis, Analytical Chemistry, General Chemistry, Experiments on General Chemistry; Graduate Course: Modern Instrumental Analysis;

(2) Writing two textbooks for undergraduates: General Chemistry (2nd version), Medical General Chemistry;

(3) Speaker of Analytical Chemistry-High quality resource sharing undergraduate course of Jiangxi Province, and Modern Instrumental Analysis-Excellent graduate course of Jiangxi Province;

Speaker of General Chemistry-Excellent online developing course of Jiangxi Province, and General Chemistry-First-class online and offline undergraduate course of Jiangxi Province.

Research fields:

My research interests mainly focus on the development of simple and highly efficient opto/electroanalytical methods based on novel nanomaterials to tackle the bottlenecks of accurate measurement of key chemicals in complex biological systems. I have published 50+ research articles being cited 1600+ times, and hold 3 patents. H-index = 26.

(1) Multimodal analysis based on carbon-based and noble metal nanoparticles/nanoclusters;

(2) Biosensing and bioimaging based on luminescent metal-organic frameworks;

(3) Design, synthesis, and analytical applications of Functional nanozymes.

Research projects：

(1) In vivo analysis using coordination polymer-based ratiometric fluorescent probes, 21505067, the National Natural Science Foundation of China;

(2) Functionalization of metal-organic frameworks-based nanozymes for constructing highly selective biosensors, 21864018, the National Natural Science Foundation of China;

(3) Design and systhesis of metal-organic framework reaction-based fluorescent probes for detection and imaging of reactive sulfur species, 22164013, the National Natural Science Foundation of China;

(4) Construction of ESIPT-active metal-organic framework-based fluorescent probes for biosensing and bioimaging, 20212BAB203033, the Natural Science Foundation of Jiangxi Province, China;

(5) Noble metal nanoclusters-based nanozymes for bioanalysis, GJJ60203, Scientific Research Foundation of Education Commission of Jiangxi Province, China.

Awards and Honors：

Representative papers and patents：

(1) Representative papers

1. Shan Huang, Ying Liu, Pengcheng Huang*, Fang-Ying Wu*, Lanqun Mao, Exploring Zr-based Metal–Organic Frameworks as Smart Electrochromic Sensors by Coordination-Driven Surface Engineering, Chem. Eur. J., 2023, 29, e202300263.

2. Chunqi Cai, Qingqing Chen, Hongyan Su, Pengcheng Huang*, Junjie Mao*, Fang-Ying Wu, Single copper sites dispersed on metal−organic frameworks boost the degradation of nerve agent simulants, SCIENCE CHINA Materials, 2023, 66(6), 2475–2482.

3. Hongyan Su, Pengcheng Huang*, and Fang-Ying Wu, Visualizing the degradation of nerve agent simulants using functionalized Zr-based MOFs: from solution to hydrogels, Chem. Commun., 2021, 57, 11681-11684.

4. Nan Gao, Yunfang Zhang, Pengcheng Huang*, Zhehao Xiang, Fang-Ying Wu*, Lanqun Mao, Perturbing Tandem Energy Transfer in Luminescent Heterobinuclear Lanthanide Coordination Polymer Nanoparticles Enables Real-Time Monitoring of Release of the Anthrax Biomarker from Bacterial Spores, Anal. Chem., 2018, 90 (11), 7004–7011.

5. Pengcheng Huang*, Fangying Wu*, Lanqun Mao, Target-triggered switching on and off the luminescence of lanthanide coordination polymer nanoparticles for selective and sensitive sensing of copper ions in rat brain, Anal. Chem., 2015, 87, 6834−6841.

6. Nan Gao, Zhipeng Zhang, Yi Xiao, Pengcheng Huang*, Fang-Ying Wu*, Integrated ratiometric luminescence sensing strategy based on encapsulation of guests in heterobinuclear lanthanide coordination polymer nanoparticles for glucose detection in human serum, Talanta, 2023, 265, 124854.

7. Yujuan Qin, Pengcheng Huang*, Fang-Ying Wu*, Histamine-responsive dye-incorporated carbon dots for visual monitoring of food spoilage, Sensors and Actuators: B. Chemical, 2022, 365, 131911.

8. Yuting Gao, Yan Wu, Pengcheng Huang*, Fang-Ying Wu*, Carbon Dot-Encapsulated Plasmonic Core-Satellite Nanoprobes for Sensitive Detection of Cancer Biomarkers via Dual-Mode Colorimetric and Fluorometric Immunoassay, ACS Appl. Nano Mater., 2022, 5 (8), 11539-11548.

9. Shan Huang, Xinhao Han, Ying Liu, Pengcheng Huang*, Ke-Yu Deng*, Fang-Ying Wu*, A reversible fluorescent probe based on a redox-switchable excited-state intramolecular proton-transfer active metal-organic framework for detection and imaging of highly reactive oxygen species in live cells, ACS Appl. Bio Mater., 2022, 5, 5165−5173.

10. Tian-Tian Cai, Yao Tian, Pengcheng Huang*, Fang-Ying Wu*, Dual-product synergistically enhanced ratiometric fluorescence assay for alkaline phosphatase activity using a core-shell lanthanide-based nanoprobe, Anal. Chim. Acta, 2022, 1235, 340550.

11. Zhipeng Zhang, Ying Liu, Pengcheng Huang*, Fang-Ying Wu*, Lihua Ma, Polydopamine molecularly imprinted polymer coated on a biomimetic iron-based metal–organic framework for highly selective fluorescence detection of metronidazole, Talanta, 2021, 232, 122411.

12. Pengcheng Huang, Ying Liu, Avishek Karmakar, Qikun Yang, Jing Li*, Fang-Ying Wu, Ke-Yu Deng, Tuning excited-state intramolecular proton transfer (ESIPT) based luminescence of metal-organic frameworks by metal nodes toward versatile photoluminescent applications, Dalton Transactions, 2021, 50, 6901-6912.

13. Yujuan Qin, Yongju Bai, Pengcheng Huang*, Fang-Ying Wu*, Dual-Emission Carbon Dots for Ratiometric Fluorescent Water Sensing, Relative Humidity Sensing, and Anticounterfeiting Applications, ACS Appl. Nano Mater., 2021, 4, 10, 10674-10681.

14. Bo-Wen Liu, Pengcheng Huang*, Fang-Ying Wu*, Rapid visual detection for nitroreductase based on the copper ions-induced and NADH-mediated aggregation of gold-silver alloy nanoparticles, Talanta, 2021, 234, 122681.

15. Zhipeng Zhang, Yao Tian, Pengcheng Huang*, Fang-Ying Wu*, Using target-specific aptamers to enhance the peroxidase-like activity of gold nanoclusters for colorimetric detection of tetracycline antibiotics, Talanta, 2020, 208, 120342.

16. Yang-Yang Wu#, Pengcheng Huang#, Fang-Ying Wu*, A label-free colorimetric aptasensor based on controllable aggregation of AuNPs for the detection of multiplex antibiotics, Food Chemistry, 2020, 304, 125377 (ESI highly cited paper).

17. Hao Fang, Ning Wang, Lin Xie, Pengcheng Huang*, Ke-Yu Deng, Fang-Ying Wu*, An excited-state intramolecular proton transfer (ESIPT)-based aggregation-induced emission active probe and its Cu(II) complex for fluorescence detection of cysteine, Sensors and Actuators B: Chemical, 2019, 294, 69-77.

18. Zhipeng Zhang, Jiayu Feng, Pengcheng Huang*, Sha Li, Fang-Ying Wu*, Ratiometric fluorescent detection of phosphate in human serum with functionalized gold nanoclusters based on chelation-enhanced fluorescence, Sensors and Actuators B: Chemical, 2019, 298, 126891.

19. Peng-Cheng Huang, Nan Gao, Jian-Fang Li, Fang-Ying Wu*, Colorimetric detection of methionine based on anti-aggregation of gold nanoparticles in the presence of melamine, Sensors and Actuators B: Chemical, 2018, 255, 2779–2784.

20. Nan Gao, Jian Huang, Liyuan Wang, Jiayu Feng, Pengcheng Huang*, and Fangying Wu, Ratiometric fluorescence detection of phosphate in human serum with a metal-organic frameworks-based nanocomposite and its immobilized agarose hydrogels, Applied Surface Science, 2018, 459, 686–692.

21. Chengliang Ye, Yujuan Qin, Pengcheng Huang*, Anfeng Chen, Fang-Ying Wu*, Facile synthesis of carbon nanodots with surface state-modulated fluorescence for highly sensitive and real-time detection of water in organic solvents, Anal. Chim. Acta, 2018, 1034, 144-152.

22. Bo-Wen Liu, Peng-Cheng Huang*, Jian-Fang Li, Fang-Ying Wu*, Colorimetric detection of tyrosinase during the synthesis of kojic acid/silver nanoparticles under illumination, Sensors and Actuators B: Chemical, 2017, 251, 836–841.

23. Jiayu Feng, Pengcheng Huang*, Fang-Ying Wu*, Gold-platinum bimetallic nanoclusters with enhanced peroxidase-like activity and their integrated agarose hydrogel-based sensing platform for the colorimetric analysis of glucose level in serum, Analyst, 2017, 142, 4106-4115.

24. Jiayu Feng#, Pengcheng Huang#, Shuizhen Shi, Ke-Yu Deng, Fang-Ying Wu, Colorimetric detection of glutathione in cells based on peroxidase-like activity of gold nanoclusters: A promising powerful tool for identifying cancer cells, Anal. Chim. Acta, 2017, 967, 64-69.

25. Pengcheng Huang, Wenjie Ma, Ping Yu, Lanqun Mao*, Dopamine-Directed In-Situ and One-Step Synthesis of Au@Ag Core-Shell Nanoparticles Immobilized to Metal-Organic Framework for Synergistic Catalysis, Chem. Asian. J., 2016, 11, 2705–2709.

26. Pengcheng Huang*, Sha Li, Nan Gao, Fangying Wu*, Toward selective, sensitive, and discriminative detection of Hg2+ and Cd2+ via pH-modulated surface chemistry of glutathione-capped gold nanoclusters, Analyst, 2015, 140, 7313–7321.

(2) Patents

1. Pengcheng Huang, Nan Gao, Jiayu Feng, Jian Huang, Fang-Ying Wu*, An analytical method for ratiometric fluorescence detection of phosphate with a metal-organic frameworks-based nanocomposite, ZL201711445910.0;

2. Lanqun Mao, Lifen Yang, Pengcheng Huang, Preparation of one kind of nanomaterials with biosensing function, ZL2011201110001660.8;

3. Lanqun Mao, Lifen Yang, Pengcheng Huang, Preparation of one kind of water-soluble CdS quantum dots, 201210114801.1.