Name: Xun Tuo

Gender: Male

Job title: Senior laboratory engineer

Email Address: tuoxun@ncu.edu.cn

Education and Work Experience ：

2007 -- present: School of Chemistry and Chemical Engineering, Nanchang University, Senior laboratory engineer.

2010.09~2015.07: University of Chinese Academy of Sciences, doctoral degree

Teaching：Since taking up his post, he has been responsible for the management of about undergraduate Organic Chemistry experiments in Nanchang university.

Research fields: the toxicity mechanism of microcystins to human health, the binding mode of protein-ligand complex.

Research projects：

1. National Natural Science Foundation of China, 31860153, Analysis of potential toxicity mechanisms of hepatic lipidmetabolism disorders induced by Microcystin-LR using proteomics and computational simulation approach.

2. Natural Science Foundation of Jiangxi Province, 20202BAB203009, Revealing the potential target proteins of microcystin-LR and their roles inthe toxicity mechanisms of MC-LR on mammals.

Awards and Honors：

Representative papers and patents：

1) Ma XL, Kuang L, Wang XW, Zhang ZH, Chen CL, Ding P, Chi BZ, Xu JY, Tuo X*. Investigation on the interaction of aromatic organophosphate flame retardants with human serum albumin via computer simulations, multispectroscopic techniques and cytotoxicity assay. International journal of biological macromolecules,2023,247: 125741

2) Zhou BJ, Zhou H, Xu LL, Cai RR, Chen CL, Chi BZ, Tuo X*. An insight into the interaction between Indisulam and human serum albumin: Spectroscopic method, computer simulation and in vitro cytotoxicity assay. Bioorganic Chemistry, 2022, 127:106017.

3) Huang XJ, Zhang SY, Li YS, Yang X, Li N, Zeng GF, Chen FP, Tuo X*. Insight into the binding characteristics of rutin and alcohol dehydrogenase: Based on the biochemical method, spectroscopic experimental and molecular model. Journal of Photochemistry and Photobiology B: Biology, 2022,228:112394.

4) Lv XL, Jiang Z, Zeng GF, Zhao SJ, Li N, Chen FP, Huang XJ, Yao J, Tuo X*. Comprehensive insights into the interactions of dicyclohexyl phthalate and its metabolite to human serum albumin. Food and Chemical Toxicology, 2021, 155:112407.

5) Chen FP, Zhou LK, Zhou BJ, Zhang SY, Ma XL, Zhou H, Tuo X*. Elucidation on the interaction between transferrin and ascorbic acid: A study based on spectroscopic analysis, molecular docking technology, and antioxidant evaluation. Journal of Molecular Liquids, 2022, 360:119413.

6) Li N, Yang X, Chen FP, Zeng GF, Zhou LK, Li XK, Tuo X*. Spectroscopic and in silico insight into the interaction between dicofol and human serum albumin. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 264:120277.

7) Liao TC, Zhang, Y, Huang XJ, Jiang Z, Tuo X*. Multi-spectroscopic and molecular docking studies of human serum albumin interactions with sulfametoxydiazine and sulfamonomethoxine. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 246:119000.